Panarum

Technology

Our patented technology Proteoral®

Proteoral® is the recombinant protein that renders therapeutic proteins orally:

It is the universal oral delivery device that safely transports active therapeutic protein in gastroprotectants capsules in the bloodstream.
Therapeutic polypeptides and Proteoral pass through stomach fluids in gastroprotectants capsules hermetically sealed.
In the small intestine, Proteoral® and the active therapeutic protein are released colocally.
Proteoral® opens the intercellular junctions of the intestinal epithelium and carries out the innocuous paracellular transepithelial passage of the active therapeutic proteins.
More than 75% of the oral dose of the active therapeutic protein is absorbed in the bloodstream.
The absorbed therapeutic protein carries out its biological activity at the site of action.

PROTEORAL® IS COMBINED WITH DIFFERENT MOLECULES

In our preclinical studies, consistently more than 75% of the oral dose of follicle stimulating hormone and Proteoral in hermetically sealed gastroprotective capsules are absorbed in the bloodstream and their therapeutic activity is successfully performed.

BENEFITS OF TAKING THERAPEUTIC PROTEINS WITH PROTEORAL®

Sales increased.
Lower manufacturing costs.
Oral Therapeutic Proteins are fully absorbed in the bloodstream.
Successful therapies with greater patient adherence.
Patent protected technology.
Eco-Friendly Business.
Easy to Take.

PROTEORAL’S SUCCESSFUL MODE OF ACTION

Proteoral® and the therapeutic protein encapsulated in gastroprotectants pills, pass through the stomach and are released colocally in the small intestine. There, Proteoral® safely opens the intercellular junctions of the intestinal epithelium and transports the active therapeutic proteins in the bloodstream. Therapeutic proteins are distributed in their site of action and successfully carry out their therapeutic activity.

Applications

PROTEORAL® AND ITS THERAPEUTIC AREAS

Proteoral® is successfully applied in different therapies that use proteins:

Oral gonadotropins in fertility therapies.
Oral insulin in insulin-dependent diabetes therapy.
Monoclonal antibodies and other oral proteins.

STRATEGIC ALLIANCE AGREEMENTS

Thanks to Proteoral® and our strategic alliance agreements with world leaders in the biopharmaceutical industry and technology, oral therapeutic proteins are manufactured and commercialized worldwide on a large scale with the highest standards of excellence and quality. In our agreements we are totally successful throughout our value chain.