Most therapeutic biological products are injectable. However, oral medications are the patients first choice of drug intake. Proteoral is the solution as it transports biological active pharmaceutical ingredients through the intestine, using pills instead of shots. Proteoral is friendly to humans and the planet.
A homogeneous solution of your biological pharmaceutical active ingredient and the Proteoral excipient is obtained.
2 | Powder
A homogeneous powder suitable for the encapsulation of your biological pharmaceutical active ingredient and the Proteoral excipient is obtained.
3 | Encapsulated
Your active ingredients and Proteoral are encapsulated in capsules that protect from stomach action and are quick - release at the small intestine.The active ingredient released is rapidly absorbed in the intestine with Proteoral into the bloodstream reaching its site of action.
4 | Medicinal product
Be a game changer in your market with your oral biological product.
Safety for your company and patients
Safe and effective Proteoral
Our versatile formulation platform protects your active ingredients in capsules and releases them in the small intestine. The active ingredient is absorbed with Proteoral into the bloodstream. .Initial non-clinical trial had demonstrated that Proteoral is safe and effective.
Why choose us
Proteoral is a recombinant protein produced by biotechnology with low manufacturing costs. Its mechanism of action is completely innocuous, it opens the intercellular junctions of the intestine and transports your product to the bloodstream, reaches the target site and fulfills its therapeutic action. Be a pioneer in your segment with your oral biological medicinal product!
High Quality Oral Biologics medicinal products by Design.
Faster pharmacokinetic and pharmacodynamic studies.
Manufacture in accordance to GLP/GMP preclinical and clinical phases standards
Technical transfer to the manufacturing site Supported
Production and on-site troubleshooting supported.
Friendly to humans and the planet.
We benefit the lives of humans by transforming the industry through oral biological medicines.
To be a prefered partner in the pharmaceutical industry and medicine by incorporating new products and scientific discoveries into the market.
Through our ethics, commitment to medicine, and global vision, we contribute to Wellness and Health with a global impact.
We connect, inspire, empower technologists and scientists become the innovations found in the world’s most impactful companies.
Top Pre-Accelerator & Incubator In Silicon Valley.
We partner with those who rebuild society through empathy and technology.
Fondo Fiduciario Para el Desarrollo de Capital Emprendedor (FONDCE).
Centro de Medicina Comparada
Universidad del Litoral
Universidad de Buenos Aires
Frequently Asked Questions
What is the biological activity of Proteoral? Proteoral is a pore-forming protein opening the intercellular junctions of the small intestine.
What is the type of transportation? Biologics active ingredients are transported by paracellular transepithelial passage through the small intestine and absorbed into the bloodstream.
What are the molecules it transports? Proteoral can transport macromolecules: Hormones, monoclonal antibodies, peptides, polysaccharides and other macromolecules.
Is there any size limit for loading? Proteoral transports macromolecules from peptides from 5 Kda to more than 147 Kda.
When does Proteoral have its peak activity? The activity of Proteoral begins 20 minutes after the release of the product in the intestine, and the greatest absorption is achieved 2 hours after oral -administration.
What is the region of maximum absorption in the intestine? The region of maximum absorption is the duodenum and jejunum-ileum in the small intestine.
Proteoral exported to a multinational Company in Darmstadt, Germany
Safety and efficacy functionality studies of Proteoral are performed in an international interlaboratory collaboration between...